Impairment of Circulating CD4+CD25+GARP+Regulatory T Cells in Patients with Acute Coronary Syndrome
نویسندگان
چکیده
منابع مشابه
Impairment of Circulating CD4⁺CD25⁺GARP⁺ regulatory T cells in patients with acute coronary syndrome.
BACKGROUND Atherosclerosis (AS) is an inflammatory and immune disease. Regulatory T cells (Tregs) suppress the activation of T cells and have been shown to play a protective role during the pathogenesis of AS. However, specific markers for Tregs are lacking. Recently, glycoprotein A repetitions predominant (GARP) was discovered as a specific marker of activated Tregs, and we therefore utilized ...
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The aim of this study was to investigate the changes of circulating CD4(+)CD25(+)CD127(low) regulatory T cells (Treg) in patients with acute coronary syndrome (ACS) and its significance. The experiment was divided into three groups: ACS (48 patients), stable angina pectoris (SAP) (24 patients), and normal controls (24 subjects). The CD4(+)CD25(+)CD127(low) Treg cell counts were tested by flow c...
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ژورنال
عنوان ژورنال: Cellular Physiology and Biochemistry
سال: 2014
ISSN: 1421-9778,1015-8987
DOI: 10.1159/000358639